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sacral neuromodulation
podcast series


Welcome to our InterStim™ Therapy clinical podcast series

This series of podcasts is to expand your knowledge and improve your understanding of InterStim™ Therapy, ultimately leading to improved patient outcomes and satisfaction. With these podcasts, you’ll be able to keep up with the latest Pelvic Health clinical evidence, whenever and wherever you want.

Episode 4

troubleshooting and follow up - practical experience

Reprogramming and troubleshooting aim to further improve patient symptoms and ensure a comfortable delivery of the therapy. There is a logical and stepwise approach to reprogramming that can improve the outcome of InterStim™ Therapy and restore patient satisfaction.

InterStim Therapy Podcast Episode 4: Troubleshooting and follow up - a practical experience - (16:22)

InterStim Therapy Podcast Episode 4: Troubleshooting and follow up - a practical experience
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Mr. Thomas Dudding
Consultant Colorectal and Pelvic Floor Surgeon,
University Hospital Southampton,
United Kingdom

Background reading
[5] Thomas C. Dudding, Lehur PA, Sorensen M et al. Neuromodulation 2021. In press

Excel in programming with InterStim™ Therapy.

Transform experience into excellence with practical learnings from 13 internationally renowned InterStim™ experts.

InterStim™ Amplitude Study

Patients had significant reduction in OAB symptoms and increased quality-of-life with subsensory stimulation in post-implantation phase of therapy1.

Previous Episodes

Episode 1

Tined Lead Placement Optimization 

Listen to the experts on the standardization technique that optimizes the tined lead placement and by this impacting InterStim™ Therapy outcomes.


Prof. Stefan de Wachter 
Professor of Urology, Neurourology,
Incontinence and Reconstructive Urology,
Head of Urology Department
Antwerp University Hospital,

Prof. Klaus Matzel 
Professor of Colorectal Surgery, 
Head of the Section of Coloproctology,
University Hospital of Erlangen,

Background reading
[1] Matzel KE, Chartier-Kastler E, Knowles CH et al.
Neuromodulation 2017; 20:816–824.

[2] Jairam R, Marcelissen T, van Koeveringe G, van Kerrebroeck P.
Neuromodulation. 2017 Dec; 20(8):830-835.

Episode 2

the science behind programming of Interstim™ therapy

Hear from the InterStim™ Therapy expert why both sensory and motor responses have relevance during electrode placement as well as in subsequent programming, and why starting the therapy with currently used frequencies (i.e. 14 Hz) and pulse widths (i.e. 210 μs)  fall in relevant ranges and much more.


Prof. Charles Knowles
Professor of Surgery at Barts and The London School of Medicine and Dentistry,
United Kingdom

Background reading
[3] Knowles CH, de Wachter S, Engelberg S et al.
Colorectal Dis 2021;23:592–602.

Episode 3


Listen to the expert recommendations on how to standardize the post implant follow-up and make programming easier and more efficient by using 4 basic programming principles. A regular follow-up is necessary to assess and eventually optimize results, as well as to reassure patients.


Prof. Paul-Antoine Lehur
Colorectal Surgeon,
Lugano Hospital,

Background reading
[4] Lehur, P.A., et al.,
Neuromodulation, 2020. 23(8): p. 1121-1129.

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Medical education and clinical programmes can help you deliver relief even more efficiently.

A Medtronic sacral neuromodulation (SNM) patient watching birds fly across the beach after finding incontinence relief from InterStim therapy.



Matzel KE, Chartier-Kastler E, Knowles CH et al. Sacral neuromodulation: standardized electrode placement technique. Neuromodulation 2017;20:816–824. 


Jairam R, Marcelissen T, van Koeveringe G, van Kerrebroeck P. Optimal Lead Positioning in Sacral Neuromodulation: Which Factors Are Related to Treatment Outcome? Neuromodulation. 2017 Dec;20(8):830-835. doi: 10.1111/ner.12649. Epub 2017 Sep 6  


Knowles CH, de Wachter S, Engelberg S et al. The science behind programming algorithms for sacral neuromodulation. Colorectal Dis 2021;23:592–602


Lehur, P.A., et al., Programming Algorithms for Sacral Neuromodulation: Clinical Practice and Evidence-Recommendations for Day-to-Day Practice. Neuromodulation, 2020. 23(8): p. 1121-1129


Thomas C. Dudding, Lehur PA, Sorensen M et al. Neuromodulation 2021. In press


See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative and/or consult the Medtronic website at

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