Ambulatory AV synchronous pacing over time using a leadless ventricular pacemaker:
Larry A. Chinitz, M.D., FHRS, Mikhael F. El Chami, M.D., FHRS, et al.
Primary results from the AccelAV study
Sustained resting AV synchrony
85.4% and stable through three months
Improved ambulatory AV synchrony
82.6% with optimized programming
No upgrades through three months
No major complications due to pacemaker syndrome
Improved ambulatory AV synchrony with optimized programming1
Listen now to the podcast on the Micra AccelAV study from Alphons Vincent, Medtronic Medical Affairs Director for Western Europe.
To report on the performance of the Micra AV leadless ventricular pacemaker with accelerometer-based algorithms that provide AV synchronous pacing.
Prospective, single-arm, multicenter, global study
- 152 subjects from 20 centers in the U.S. and Hong Kong were implanted with a Micra AV
– 54 with complete AV block and normal sinus function (primary analysis cohort)
- 20 with complete AV block, normal sinus function, and optimized programming (Optimized sub-study cohort)
EHRA/HRS/LAHRS/APHRS position paper
which aims to review the underlying evidence, provide practical considerations for optimal use and patient selection for laeadless and extravascular CIED’s.
CED study : 3-year follow-up
Read the Micra™ CED study published in the European Heart Journal. Real-world study showing the safety and efficacy of the Micra leadless VVI pacemaker vs transvenous pacemakers.
ESC 2021 guidelines
ESC Guidelines now recommend leadless pacing for defined patient populations.4
*
Includes independently published manuscripts not sponsored by Medtronic.
References
1
Chinitz LA, El-Chami MF, Sagi V, et al. Ambulatory AV synchronous pacing over time using a leadless ventricular pacemaker: Primary results from the AccelAV study. Heart Rhythm. Published online September 5, 2022.
2
Leick A. “Largest Reach” supporting data. June 2022. Medtronic Data on file
3
Clementy N, et al. Early Experience with a Leadless Ventricular Pacemaker Providing Atrioventricular Synchronous Pacing in the Real-World Setting: Results from the Micra AV Post-Approval Registry. Presented at HRS 2022 Scientific Sessions. April 30, 2022. San Fransico
4
Glikson, M. et al. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. October 2021. European Heart Journal.
5
Nippoldt D, Whiting J. Micra Transcatheter Pacing System Device Volume Characterization Comparison. November 2014. Medtronic data on file
Brief statement
See the device manual for detailed information regarding the instructions for use, the implant procedure, indications, contraindications, warnings, precautions, and potential adverse events. If using an MRI SureScan™ device, see the MRI SureScan™ technical manual before performing an MRI. For further information, contact your local Medtronic representative and/or consult the Medtronic website at medtronic.eu.
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