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The Next Generation Of Efficiency

Arctic Front Advance ProTM Cryoballoon
Illustration of the AFA Pro Cryoballoon in the pulmonary vein.


The Arctic Front Advance Pro Cryoballoon is the latest catheter innovation in cryoablation technology. Its short-tip profile may allow for improved time-to-isolation visualization,1-6 which enables physician-tailored dosing protocols7 and may result in improved procedural efficiency, such as decreased procedure time, without compromising efficacy.1-8

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Improved Visualization of TTI May Help Drive Improved Procedure Outcomes

  • Observing time to PV isolation is facilitated by contact of the Achieve™ catheter and the muscular sleeves (which transmit PV potentials).9
  • Real-time PVI visualization has emerged as a potentially valuable parameter to estimate the quality of an ablation lesion as this is the only true tissue physiology that can be monitored.9-10
  • Shorter time to PV isolation has shown to be predictive of a durable lesion, whereas longer time to PV isolation has been associated with an increased risk of PV reconnection.10

Improved Visualization of TTI*

Designed to help improve the Achieve mapping catheter family's ability to measure time-to-isolation (TTI) by bringing the electrodes closer to the veins’ muscular sleeves

Built on a Proven Platform

Maintains the benefits proven in the 700+ peer-reviewed articles and abstracts supporting the safety and efficacy of the Arctic Front family

See the Evidence
Arctic Front Advance Pro Cryoballoon illustrating the difference in tip length.

Shortened Tip Profile*

The 40% shortened tip may allow for improved catheter maneuverability in patients with smaller left atria or early PV branching.

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Arctic Front Advance Cryoballoon
Arctic Front Advance Pro Cryoballoon


Arctic front advance pro cryoballoon

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Watch how the Arctic Front Advance Pro Cryoballoon, with its 40% shorter tip, achieves PVI.

Arctic Front Advance Pro Spec Sheet

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The value of Arctic Front Advance Pro Cryoballoon Catheter

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Educational Resources On Medtronic Academy

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The clinical evidence presented in this section regarding the short-tip balloon was collected using Arctic Front Advance™ ST cryoballoon catheter, the Medtronic third-generation cryoballoon, not Arctic Front Advance Pro. However, this data is relevant to Arctic Front Advance Pro as it is also a short-tip balloon.


Bench data.

Medtronic data on file.


Fürnkranz A, Bologna F, Bordignon S, et al. Procedural characteristics of pulmonary vein isolation using the novel third-generation cryoballoon. Europace. December 2016;18(12):1795-1800.


Mugnai G, de Asmundis C, Hünük B, et al. Improved visualisation of real-time recordings during third generation cryoballoon ablation: A comparison between the novel short-tip and the second generation device. J Interv Card Electrophysiol. September 2016;46(3):307-314.


Heeger CH, Wissner E, Mathew S, et al. Short tip-big difference? First-in-man experience and procedural efficacy of pulmonary vein isolation using the third-generation cryoballoon. Clin Res Cardiol. June 2016;105(6):482-488.


Pott A, Petscher K, Messemer M, Rottbauer W, Dahme T. Increased rate of observed real-time pulmonary vein isolation with third-generation short-tip cryoballoon. J Interv Card Electrophysiol. December 2016;47(3):333-339.


Aryana A, Kowalski M, O'Neill PG, et al. Catheter ablation using the third-generation cryoballoon provides an enhanced ability to assess time to pulmonary vein isolation facilitating the ablation strategy: Short- and long-term results of a multicenter study. Heart Rhythm. December 2016;13(12):2306-2313.


Sciarra L, Iacopino S, Palamà Z, et al. Impact of the third generation cryoballoon on atrial fibrillation ablation: An useful tool? Indian Pacing Electrophysiol J. July-August 2018;18(4):127-132.


Aryana A, Kenigsberg DN, Kowalski M, et al. Verification of a novel atrial fibrillation cryoablation dosing algorithm guided by time-to-pulmonary vein isolation: Results from the Cryo-DOSING Study. Heart Rhythm. 2017;14(9):1319-1325.


Dahme T, et al. Time-To-Isolation Guided Dosing Leads to Reduced Procedure Duration and Fluoroscopy Time With Comparable One Year Clinical Outcomes in Cryoballoon Pulmonary Vein Isolation. Europace Abstracts Supplement, 2017.


Su, et al. Best Practice Guide for Cryoballoon Ablation in Atrial Fibrillation: The compilation experience of over 3000 Procedures. Heart Rhythm. 2015 Mar 14. pii: S1547-5271(15)00278-7.


Aryana, et al. Procedural and biophysical indicators of durable pulmonary vein isolation during cryoballoon ablation of atrial fibrillation. Heart Rhythm. 2016 Feb;13(2):424-32.

See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative and/or consult the Medtronic website at