Patient Prosthesis Mismatch (PPM) Calculator

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In Vivo Indexed Effective Orifice Area (iEOA)

 

In Vivo Indexed Effective Orifice Area (iEOA)

INDEX EFFECTIVE ORIFICE AREA (iEOA) = EOA/BSA²

Mild
iEOA > 0.85 cm2/m2

Moderate
iEOA ≤ 0.85 cm2/m2

Severe
iEOA ≤ 0.65 cm2/m2

Mortality
Risk
 

PPM Calc SVD Risk

Heart failure
rehospitalisation
 

PPM Calc SVD Risk

Structural valve degeneration (svd)
risk

PPM Calc SVD Risk

IMPORTANT NOTE: This PPM calculator tool is intended to create awareness of the risk of Patient Prosthesis Mismatch. It is not intended to provide guidance on diagnosis or treatment.

1

Herrmann HC, Daneshvar SA, Fonarow GC, et al. Prosthesis-Patient Mismatch in Patients Undergoing Transcatheter Aortic Valve Replacement: From the STS/ACC TVT Registry. J Am Coll Cardiol. December 4, 2018;72(22):2701-2711

2

Flameng W, Herregods MC, Vercalsteren M, Herijgers P, Bogaerts K, Meuris B. Prosthesis- patient mismatch predicts structural valve degeneration in bioprosthetic heart valves. Circulation. May 18, 2010;121(19):2123-2129. 

3

Kappetein AP, Head SJ, Généreux P, et al. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document (VARC-2). Eur J Cardiothorac Surg. November 2012;42(5):S45-S60.

4

Head SJ, Mokhles MM, Osnabrugge RL, et al. The impact of prosthesis-patient mismatch on long-term survival after aortic valve replacement: a systematic review and meta-analysis of 34 observational studies comprising 27 186 patients with 133 141 patient-years. Eur Heart J. June 2012;33(12):1518-1529.

5

Kappetein AP, Head SJ, Généreux P, et al. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document (VARC-2). Eur J Cardiothorac Surg. November 2012;42(5):S45-S60.

* Herrmann HC, Daneshvar SA, Fonarow GC, et al. Prosthesis-Patient Mismatch in 62,125 Patients Following Transcatheter Aortic Valve Replacement: From the STS/ACC TVT) Registry. J Am Coll Cardiol. Published online September 18, 2018.