ABOUT THE THERAPY TRANSCATHETER AORTIC VALVE IMPLANTATION (TAVI)

Indications, Safety, and Warnings   Indications, Safety, and Warnings 

A MINIMALLY INVASIVE ALTERNATIVE FOR SEVERE AORTIC STENOSIS

TAVR incision locations

A changing paradigm in the management of patients with severe aortic stenosis, transcatheter aortic valve implantation (TAVI) is a minimally invasive, catheter-based procedure to replace the aortic valve. Prior to TAVI, treatment options were limited to:

  • Temporarily improving valve function and easing symptoms by prescribing medication and performing a BAV procedure
  • Replacing the diseased valve in an open-heart surgery (surgical aortic valve implantation)

TAVI does not require open-heart surgery. Instead, with TAVI, the heart is accessed via an artery. There are three access options:

  1. Transfemoral
  2. Subclavian
  3. Direct aortic

WHAT HAPPENS DURING THE TRANSCATHETER AORTIC VALVE IMPLANTATION?

A transcatheter aortic valve implantation (TAVI) procedure is less invasive than open heart surgery. The entire procedure typically takes approximately 1-2 hours. Your heart team will determine whether you should have a mild sedative or general anesthesia.

 

Tavi valve illustration image

Using imaging and a delivery system, the physician threads the compressed bioprosthetic heart valve through the catheter and positions it within the diseased valve.

Tavi valve illustration image

After positioning the bioprosthetic valve, the physician begins deploying the valve; the middle image below shows a partially expanded valve. 

Tavi valve illustration image

When deployment is complete, the bioprosthetic valve is fully expanded within the diseased native valve.

After testing the new valve function, the physician removes the catheter and closes the incision.

Understanding the TAVI procedure.
Watch this animation about the TAVI procedure.

AN EXCELLENT OPTION from low to increased surgical risk

TAVI may be an excellent option for certain patients with severe symptomatic aortic stenosis who may have increased risks associated with surgical aortic valve implantation (SAVI).1

Without intervention, this patient population's survival rate is approximately 50% at two years.2

The Evolut™ and Corevalve™ TAVI platforms have shown exceptionally strong safety and performance throughout years of clinical study results and across the surgical risk spectrum.

View Study Data

POTENTIAL BENEFITS

The Evolut TAVI platform’s supra-annular valve design delivers large EOAs (effective orifice area) and low single-digit gradients resulting in industry-leading hemodynamics.

POTENTIAL RISKS

Most medical procedures have risks. The Medtronic TAVI procedure’s most serious risks include:

  • Death
  • Stroke
  • Serious damage to the arteries
  • Serious bleeding
  • Need for permanent pacemaker

LEARN MORE ABOUT AORTIC STENOSIS AND THE EVOLUT™ TAVI



The Medtronic Aortic Stenosis Evolut™️ TAVI application provides health care professionals an educational augmented reality experience, supporting patient conversations about the progression of the disease and treatment need.

A TIMELY REFERRAL MAY SAVE LIVES

Symptoms can develop insidiously and may often go unrecognized by patients and their physicians. Many patients who state they have no symptoms may be subconsciously limiting their exercise to avoid symptoms.4

After developing symptomatic heart failure, without treatment, the average patient survival is two years.3

Since no effective medical therapy to reduce or reverse aortic stenosis progression is available, the only treatment option is valve replacement.1

References

1

Everett RJ, et al. Timing of intervention in aortic stenosis: a review of current and future strategies. Heart Epub 2018 doi:10.1136/ heartjnl-2017-312304

2

Modified from Blase A. Carabello, Introduction to Aortic Stenosis, Circulation Research. 2013; Volume: 113, Issue: 2, Pages: 179-185, DOI: (10.1161 CIRCRESAHA.113.300156)

3

Lester SJ, Heilbron B, Gin K, Dodek A, Jue J. The natural history and rate of progression of aortic stenosis. Chest. April 1998;113(4):1109-1114.

4

McCarthy CP, Phelan D, Griffin B. When does asymptomatic aortic stenosis warrant surgery? Assessment techniques. Cleve Clin J Med. April 2016;83(4):271-280.

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