Clear impact 

IN.PACTTM AV Access Trial 3 years data now released

IN.PACTTM AdmiralTM† DCB for AV Fistula
the proactive approach for AV Fistula maintenance in
end-stage renal disease (ESRD) patients.


Sustained impact

The IN.PACT™ AV Access Trial confirms the superiority of IN.PACT™ DCB (Drug-Coated Balloon) vs PTA through 36 months.

Watch Dr. Holden presenting 3 years data of IN.PACT™ AV Access Trial at Charing Cross.

Proven impact

First and only DCB AVF trial to meet primary effectiveness and safety endpoints.

New England Journal Logo
56% fewer reinterventions than PTA1

fewer reinterventions than PTA1

78% highest reported access circuit primary patency1

highest reported access circuit primary patency1

86% highest reported target lesion primary patency1*

highest reported target lesion primary patency1*

Decorative Image Doctor Speaking

Big impact

IN.PACT™ Admiral™ for AV Fistula is a one-of-a-kind drug coated balloon that’s uniquely designed to address AV Access procedures needs:

  • Big diameters (up to 12mm) to increase treatment options
  • Short shaft to save procedure time

Unique impact

Thanks to its unique drug-coated formulation, IN.PACT™ DCB (Drug-Coated Balloon) treats the causes of fistula stenosis, not just the symptoms. Combining an anti-proliferative drug and an excipient, it offers the highest reported primary patency of any DCB.1*

 Additional resources

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Lookstein RA, et al. Drug-Coated Balloons for Dysfunctional Dialysis Arteriovenous Fistulas. N Engl J Med 2020;383:733-42. DOI: 10.1056/NEJMoa1914617. Highlighted results reported at both 180 and 210 days.


Holden A., IN.PACT AV Access Trial, 3-years results. Charing Cross London 2022.



In an AV DCB study.

The approved product name for the drug-coated balloon is IN.PACTTM AdmiralTM Drug-Coated Balloon Catheter.

See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative and/or consult the Medtronic website at