Hancock^™ II and Hancock II Ultra^™
Bioprostheses for Heart Valve Replacement

The Hancock II and Hancock II Ultra are for patients who require replacement of their native or prosthetic aortic and/or mitral valves. First introduced in the 1980s, Hancock II is a second-generation valve with more than 25 years of clinical experience.

Hancock II and Hancock II Ultra bioprostheses on white background

Alert Indications, Safety, and Warnings

Overview

Tested, Trusted

Our second-generation bioprosthesis is designed for use in both aortic and mitral positions.

The Hancock II valve has stood the test of time. First introduced in the 1980s, it has been tested, studied, and earned the trust of cardiac surgeons around the world. After dozens of years and improvements along the way, there are scores of reasons to use this valve with your patients.

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Product Details

30+ Years Delivering Consistent
Performance and Results

With more than 30 years delivering consistent performance and clinical results, you can feel confident procedure after procedure.

AORTIC 97.8% freedom from SVD at 20 years^*1
MITRAL 85% freedom from SVD at 15 years²

Durability

Published clinical experience demonstrates impressive long-term performance in all age groups for both the aortic and mitral valve¹. Additional factors that may contribute to durability are:

T6 (sodium dodecyl sulfate) anti-calcification treatment is applied in order to mitigate the absorption of calcium in the leaflets
Next-generation flexible polymer stent allows for absorption of stress produced during the cardiac cycle
Two-step, low-pressure fixation process

Ease of Implant

Our innovative Cinch^™ implant system further capitalizes on the valve’s flexible stent to facilitate valve implantation, particularly through a tight sinotubular space. It also:

Improves overall visualization
Has stent posts that deflect to allow for easier knot tying near the posts in aortic replacements
Helps prevent suture looping
Facilitates minimally invasive procedures
Protects tissue from inadvertent damage

Hancock II Cinch implant system on white background

Maximum Flow

The Hancock II valve is designed to allow the maximum amount of blood to flow through it.

The sewing ring is mounted flush with the inflow edge of the scalloped stent allowing the bioprosthesis to be positioned completely superior to the annulus.
The internal diameter of the valve aligns with the patient’s annulus allowing for a larger available flow area.
The valve design allows blood to flow through the annulus encountering only tissue, not obstructive components such as the stent and sewing ring.

Hancock II valve design that allows maximum blood flow

Suitable for Future Interventions

Valve dimensions and geometry enable future valve-in-valve (ViV) replacements.

Radiopaque annulus ring and stent post markers provide visible, distinct guidelines during ViV procedures.
MR conditional, nonmetallic frame mitigates risk of corrosion between SAV and TAV stent materials.
Interior-mounted leaflets mitigate potential risk of coronary obstruction.

Product Specifications and Ordering Information

Hancock II Aortic Valve, Model T505

Hancock II Model T505 configuration with sizing detail illustration

Order Number	Valve Size (Stent O.D.^†) (± 0.5 mm)	Orifice Diameter (Stent I.D.) (± 0.5 mm)	Suture Ring Diameter (± 1 mm)	Valve Height (± 0.5 mm)	Aortic Protrusion (± 0.5 mm)
	(A)	(B)	(C)	(D)	(E)
T505C221	21	18.5	27.0	15.0	12.0
T505C223	23	20.5	30.0	16.0	13.5
T505C225	25	22.5	33.0	17.5	15.0
T505C227	27	24.0	36.0	18.5	15.5
T505C229	29	26.0	39.0	20.0	16.0

Hancock II Mitral Valve, Model T510

Hancock II Model T510 configuration with sizing detail illustration

Order Number	Valve Size (Stent O.D.^†) (± 0.5 mm)	Orifice Diameter (Stent I.D.) (± 0.5 mm)	Suture Ring Diameter (± 1 mm)	Valve Height (± 0.5 mm)	Aortic Protrusion (± 0.5 mm)
	(A)	(B)	(C)	(D)	(E)
T510C25	25	22.5	33.0	18.0	13.5
T510C27	27	24.0	35.0	19.0	14.0
T510C29	29	26.0	38.0	20.5	15.5
T510C31	31	28.0	41.0	22.0	17.0
T510C33	33	30.0	43.0	23.0	17.5

Hancock II Ultra Aortic Valve, Model T505

Hancock Ultra II Model T505 configuration with sizing detail illustration

Order Number	Valve Size (Stent O.D.^†) (± 0.5 mm)	Orifice Diameter (Stent I.D.) (± 0.5 mm)	Suture Ring Diameter (± 1 mm)	Valve Height (± 0.5 mm)	Aortic Protrusion (± 0.5 mm)
	(A)	(B)	(C)	(D)	(E)
T505U221	21	18.5	26.0	15.0	12.0
T505U223	23	20.5	28.0	16.0	13.5
T505U225	25	22.5	30.0	17.5	15.0
T505U227	27	24.0	32.0	18.5	15.5
T505U229	29	26.0	34.0	20.0	16.0

Hancock II Bioprosthesis Accessories

Order Number	Description
T7610HKA	Tray, Accessory, Hancock II, Aortic
T7605HKM	Tray, Accessory, Hancock II, Mitral
T7505UX	Tray, Accessory, Hancock II Ultra, Supra-X Aortic Sizer Set
7505UX	Hancock II Ultra, Supra-X Aortic Sizer Set
7639	Handle (234 mm length) pliant, without locknut handle to be used with Hancock II, Hancock II Ultra prostheses
7639XL	Handle (368 mm length) pliant, without locknut handle to be used with Hancock II, Hancock II Ultra prostheses
7505SET	Hancock II Aortic Obturator Set (no handles, no tray)
7510SET	Hancock II Mitral Obturator Set (no handles, no tray)

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Additional Resources

Medical Education

Training, education, and collaboration on the treatment of mitral and tricuspid valve disease.

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For patients over age 65.

^†

Equivalent to annulus diameter.

References

David TE, Armstrong S, Maganti M. Hancock II bioprosthesis for aortic valve replacement: the gold standard of bioprosthetic valves durability? Ann Thorac Surg. September 2010;90(3):775-781.

Rizzoli G, Mirone S, Ius P, et al. Fifteen-year results with the Hancock II valve: a multicenter experience. J Thorac Cardiovasc Surg. September 2006;132(3):602-609, 609.e1-4.

Wright JTM, Eberhardt CE, Gibbs ML, Saul T, Gilpin CB. Hancock II: an improved bioprosthesis. In: Cohn LH, Gallucci V, eds. Cardiac Bioprostheses. New York: Yorke Medical Books; 1982:424-444.

Hancock™ II and Hancock II Ultra™ Bioprostheses for Heart Valve Replacement