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Comparison of Adaptix™ and Capstone testing per ASTM F2077and ASTM F2267.
Based on surface area measurement.
Based on engineering principles.
Medtronic Internal Report: Catalyft ™PL Implant/Instrument Design Validation (Anatomical and Navigation Simulated Use) Report. Document GC17012_TP_007 RPT, version B. Revision date: 02 05 2021
Based on six peer-reviewed, published in vitro studies on Titan surface technology:
I. Matteson, J.L., Greenspan, D.C., Tighe, T.B., Gilfoy, N., Stapleton, J.J. Assessing the hierarchical structure of titanium implant surfaces. J Biomed Mater Res B. [In Press] EPub29 May 2015.
II. Olivares-Navarrete, R., HyzyS.L., Gittens, R.A., Schneider, J.M., Haithcock, D., Ullrich, P., Schwartz, Z., Boyan, B.D. Rough titanium alloys regulate osteoblast production of angiogenic factors. Spine J. 2013 Nov; 13(11):1563-70.
III. Gittens, R.A., Olivares-Navarrete, R., Schwartz, Z., Boyan, B.D. Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants. Acta Biomater2014 Aug; 10(8): 3363-3371.
IV. Olivares-Navarrete, R., HyzyS.L., Gittens, R.A., Berg, M.E., Schneider, J.M., Hotchkiss, K., Schwartz, Z., Boyan, B. D. Osteoblast lineage cells can discriminate microscale topographic features on titanium-aluminum-vanadium surfaces. Ann Biomed Eng. 2014 Dec; 42(12): 2551-61.
V. Olivares-Navarrete, R., HyzyS.L., Slosar, P.J., Schneider, J.M., Schwartz, Z., Boyan, B.D. Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors. Spine. 2015 Mar; 40(6): 399-404.
VI. Banik, B., Riley, T., Platt, C., Brown, J. Human mesenchymal stem cell morphology and migration on microtextured titanium. Front BioengBiotechnol. 2016 May; 4(41) doi: 10.3389/fbioe.2016.00041.