ADAPTIX™ INTERBODY SYSTEM Interbody Fusion Device with Titan nanoLOCK™
Surface Technology for PLIF and TLIF Procedures

Adaptix™ interbody system offers a robust design for increased strength,¹ easy insertion, subsidence resistance,^2,3 and incorporates Titan nanoLOCK™ surface technology for proven bone growth.*

Close up of the Adaptix interbody device.

Alert Indications, Safety, and Warnings

Overview

MEET ADAPTIX™

Trusted design, enhanced features
Science-backed nano surface technology*
Spine navigation efficiency and confidence

The Adaptix interbody system in use during spinal fusion procedure.

PRODUCT DETAILS

TRUSTED DESIGN, ENHANCED FEATURES

The Adaptix™ titanium spinal cage combines the trusted features of the Capstone™ spinal system, with several design enhancements.

Close up of the Adaptix interbody device features.

1. Honeycomb Structure

Allows for more bony surface contact area compared to an open spinal cage design
Designed to minimize the stress load onto the endplates compared to an open spinal cage design
Designed to decrease subsidence compared to an open spinal cage design
Acts as an osteoconductive scaffold for bony growth into the spinal implant

2. Open Graft Windows

Allows for a continuous column of graft directly in contact with the endplate

3. Dolphin Nose

Aids in disc space distraction during insertion

4. Lateral Windows

Allows for visualization

5. Implant Width of 10mm

SCIENCE-BACKED Nano Surface Technology

Titan nanoLOCK™ surface technology is created through a subtractive manufacturing process that removes material to enable a proprietary blend of surfaces at the macro, micro, and nano levels on every surface of the implant.

Inspired by nature, this surface technology uses "biomimicry" of osteoclastic pit geometry to mimic structures involved in the bone remodeling process.

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Learn More About this Technology

Driven by science, Titan nanoLOCK™ surface technology emerged from a research-first approach to development. Multiple peer-reviewed in vitro studies resulted in Titan nanLOCK surface technology being the first to demonstrate the elements to be considered in nanotechnology as outlined by the FDA.4

Download the latest peer-reviewed articles:

pdf Implant Materials Generate Different Peri-implant Inflammatory Factors (.pdf)

pdf Osteoblast Lineage Cells Can Discriminate Microscale Topographic Features on Titanium-Aluminum-Vanadium Surfaces (.pdf)

pdf Rough Titanium Alloys Regulate Osteoblast Production of Angiogenic Factors (.pdf)

pdf Assessing the Hierarchical Structure of Titanium Implant Surfaces (.pdf)

pdf Implant Osseointegration and the Role of Microroughness and Nanostructures: Lessons for Spine Implants (.pdf)

pdf Human Mesenchymal Stem Cell Morphology and Migration on Microtextured Titanium (.pdf)

SPINE NAVIGATION EFFICIENCY AND CONFIDENCE

The navigated Adaptix™ interbody system integrates with the StealthStation™ navigation and O-arm™ imaging systems to enable pre-surgical planning, real-time navigation, and other benefits including virtual sizing of the spinal implant, 3D implant placement visualization, and confirmation of implant placement using the Surgical Synergy™ workflow.

The o-arm and StealthStation systems in the operating room.

CONTACT US FOR MORE INFORMATION

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ADDITIONAL RESOURCES

TITAN NANOLOCK™ SURFACE TECHNOLOGY

Inspired by nature, this technology incorporates a proprietary blend of surfaces. Learn more about Titan nanoLOCK™ surface technology.

EXPLORE NANOLOCK

GRAFTON^TM DBF INJECT

An osteoconductive DBM and delivery system all in one.

LEARN MORE

Comparison of Adaptix and Capstone testing per ASTM F2077and ASTM F2267

Based on surface area measurement

Based on engineering principles

⁴

FDA Guidance, Considering Whether an FDA-Regulated Product Involves the Application of Nanotechnology

Based on six peer-reviewed, published in vitro studies on Titan surface technology:

I. Matteson, J.L., Greenspan, D.C., Tighe, T.B., Gilfoy, N., Stapleton, J.J. Assessing the hierarchical structure of titanium implant surfaces. J Biomed Mater Res B. [In Press] EPub29 May 2015.

II. Olivares-Navarrete, R., HyzyS.L., Gittens, R.A., Schneider, J.M., Haithcock, D., Ullrich, P., Schwartz, Z., Boyan, B.D. Rough titanium alloys regulate osteoblast production of angiogenic factors. Spine J. 2013 Nov; 13(11):1563-70.

III. Gittens, R.A., Olivares-Navarrete, R., Schwartz, Z., Boyan, B.D. Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants. Acta Biomater 2014 Aug; 10(8): 3363-3371.

IV. Olivares-Navarrete, R., HyzyS.L., Gittens, R.A., Berg, M.E., Schneider, J.M., Hotchkiss, K., Schwartz, Z., Boyan, B. D. Osteoblast lineage cells can discriminate microscale topographic features on titanium-aluminum-vanadium surfaces. Ann Biomed Eng. 2014 Dec; 42(12): 2551-61.

V. Olivares-Navarrete, R., HyzyS.L., Slosar, P.J., Schneider, J.M., Schwartz, Z., Boyan, B.D. Implant materials generate different peri-implant inflammatory factors: PEEK promotes fibrosis and micro-textured titanium promotes osteogenic factors. Spine. 2015 Mar; 40(6): 399-404.

VI. Banik, B., Riley, T., Platt, C., Brown, J. Human mesenchymal stem cell morphology and migration on microtextured titanium. Front Bioeng Biotechnol. 2016 May; 4(41) doi: 10.3389/fbioe.2016.00041.

BRIEF STATEMENT

See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative and/or consult the Medtronic website at medtronic.eu

ADAPTIX™ INTERBODY SYSTEM Interbody Fusion Device with Titan nanoLOCK™ Surface Technology for PLIF and TLIF Procedures