Healthcare Professionals
Onyx<sup>TM</sup> Liquid Embolic System
Peripheral Embolization
You just clicked a link to go to another website. If you continue, you may go to a site run by someone else.
We do not review or control the content on non-Medtronic sites, and we are not responsible for any business dealings or transactions you have there. Your use of the other site is subject to the terms of use and privacy statement on that site.
It is possible that some of the products on the other site are not approved in your region or country.
Your browser is out of date
With an updated browser, you will have a better Medtronic website experience. Update my browser now.
The content of this website is exclusively reserved for Healthcare Professionals in countries with applicable health authority product registrations, except those practicing in France as some of the content is not in compliance with the French Advertising law N°2011-2012 dated 29th December 2011, article 34.
Click “OK” to confirm you are a Healthcare Professional.
Healthcare Professionals
Onyx<sup>TM</sup> Liquid Embolic System
Peripheral Embolization
The Onyx™ Liquid Embolic System (LES) is an ethylene vinyl alcohol (EVOH) copolymer that provides complete filling and distal penetration1 of peripheral. Its non-adhesive properties permit more distal nidus embolization without significant risk of catheter entrapment, while higher viscosities allow for controlled deployment.2
OnyxTM 18 & 34 LES: Embolization of lesions in the peripheral including arteriovenous malformations and hypervascular tumors.
OnyxTM 34L LES: Embolization of lesions in the peripheral vasculature, including endoleaks, arteriovenous malformations, portal veins, bleeding and tumors.
OnyxTM is a non-adhesive liquid embolic agent composed of EVOH dissolved in DMSO with suspended micronised tantalum powder. It is delivered through a microcatheter under fluoroscopic control.
Polymeric properties
Controlled delivery
Formulations
OnyxTM 18 and 34 LES for peripheral use:
OnyxTM 34L LES for peripheral use:
OnyxTM 34L LES packaging with 6 ml vial
OnyxTM 34L LES in 10mm vessel†
OnyxTM 34 LES in 10 mm vessel†
Product Code | OnyxTM Formulation |
---|---|
105-7200-060 |
OnyxTM 18 Peripheral Kit, 1.5 ml |
105-7200-080 |
OnyxTM 34 Peripheral Kit, 1.5 ml |
105-7315-080 |
OnyxTM 34L Kit, 1.5 ml |
105-7360-080 |
OnyxTM 34L Kit, 6 ml |
Product Code | OnyxTM LES Accessory |
---|---|
103-1205-001 |
Vortex Genie 2 120v/60Hz with 1.5mL vial attachment |
103-1205-002 |
Vortex Genie 2 240v/50Hz with 1.5mL vial attachment |
103-1205-100 |
Mixer Attachment for 6mL and 1.5mL vials |
103-1207 |
Syringe Catheter Interface Adapter |
103-1203 |
1 ml Luer-Lock Injector Syringe |
The technical manual includes indications, warnings, precautions, MRI information, and directions for use. Find it in the product labeling supplied with each device.
Non-clinical testing demonstrated that the OnyxTM Liquid Embolic System is MR conditional. A patient with this device can be scanned safely, immediately after placement under the following conditions:
Static magnetic field:
CT artifact validation in vitro using a water phantom tank to simulate body tissue and synthetic vessel document TR_NV 11300 RevA
Images are property of Medtronic.
Jose Urbano, MD, PhD Selective Arterial Embolization with Ethylene–Vinyl Alcohol Copolymer for Control of Massive Lower Gastrointestinal Bleeding: Feasibility and Initial Experience. J Vasc Interv Radiol 2014.
Ricardo Yamada, Andre Uflacker, Austin Bourgeois, Joshua D. Adams, Marcelo Guimaraes, ‘EVOH/DMSO in Peripheral Application’ in Embolization Therapy: Principles and Clinical Applications, ed. Marcelo Guimaraes, Riccardo Lencioni, and Gary P. Siskin (Philadelphia, Wolters Kluwer, 2015), 582 pp.
Perez-Higueras, A. et al. Endovascular Treatment of Cerebral AVM:Our Experience with Onyx. Interventional Neuroradiology 11:141-157,2005.
IFU 70721-001 Rev 01/13. 2 CT artifact validation in vitro using a water phantom tank to simulate body tissue and synthetic vessel Document TR_NV 11300 RevA 2013-08-20. All images property of Covidien.