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Renal Denervation for hypertension

Alert Indications, Safety, and Warnings

We're excited that you're ready to explore the opportunity renal denervation (RDN) offers to lower blood pressure. We will connect soon to keep the conversation going.

Explore patient selection resources.

Find the right patients

Explore resources for identifying patients who could benefit from the Symplicity blood pressure procedure.

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Explore data from multiple randomized controlled trials of Medtronic RDN.

Multiple randomized controlled trials

See how the Symplicity procedure has demonstrated significant and safe blood pressure reductions in two pivotal, sham-controlled trials and a real-world registry.1–3

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See how the procedure works

Learn more about the Symplicity blood pressure procedure.

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See practice resources to educate your patients about hypertension and Medtronic Renal Denervation.

Strengthen your practice

Find resources designed to help you support your patients with hypertension.

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1

Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. The Lancet 2020; Published online March 29, 2020.

2

Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. The Lancet. 2018 Jun 9;391(10137):2346-2355.

3

Mahfoud F, Mancia G, Schmieder R, et al. Three-year safety and efficacy in the Global Symplicity Registry: Impact of antihypertensive medication burden on blood pressure reduction. Presented at PCR e-course 2020.