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The Symplicity Spyral™ Renal Denervation system lowers blood pressure in a clinically meaningful way.1,2,3 It includes the Symplicity Spyral™ Multi-Electrode Renal Denervation Catheter and the Symplicity G3™ Renal Denervation RF Generator.PRODUCT DETAILS
Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. Lancet. 2018 Jun 9;391(10137):2346-2355.
Townsend RR, Mahfoud F, Kandzari DE, et al. Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL-HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial. Lancet. 2017;390;2160-2170.
Mahfoud F, Böhm M, Schmieder R, et al. Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry. European Heart Journal (2019) 0, 1–10.
All rights reserved. Medtronic, Medtronic logo and Further, Together are trademarks of Medtronic. All other brands are trademarks of a Medtronic company. ™* For distribution only in markets where the Symplicity Spyral™ multi-electrode renal denervation catheter and Symplicity G3™ renal denervation RF generator have been approved. Not for distribution in the USA, Japan or France.