Real-world cryoablation data
from >8000 patients
The 1STOP Initiative
1STOP (One Shot to PVI) is a collection of real-world PVI data from over 8,000 patients in > 50 hospitals across Italy undergoing cardiac ablation with Medtronic’s Cardiac Ablation Solutions, in particular with Arctic Front family™ of cryoablation catheters.
The goal of the initiative is to improve patient outcomes by collecting, managing, analyzing, and reporting patient data, in some cases also via dedicated patient application called “MyCryo App”.The project has supported over 20 publications on the following topics, among others:
Comparing generations of cryoballoons
Cryoablation for different patient risk profiles
Cryoablation by indication: redo, first-line persistent, paroxysmal AF
Early treatment
Optimizing patient outcomes
Imaging & time to isolation measurement
Comparing generations of cryoballoons
Comparing generations of cryoballoons
Second versus fourth generation of cryoballoon catheters
Manfrin et al., 2022, Pacing and Clinical Electrophysiology, (No = 429)
Usage of the fourth generation Arctic Front cryoballon family™ increased the rate of acute PVI recording capability and resulted in a higher rate of long-term PVI success, as demonstrated by the reduced rate of AF recurrence in comparison to the 2nd generation cohort at the 12-month follow-up period.
A comparison of acute procedural outcomes within four generations of cryoballoon catheters
Iacopino et al., 2019, Journal of Cardiovascular Electrophysiology, (No = 480)
The Arctic Front cryoballon family™ achieved significantly faster procedural ablation times in comparison to the previous generations, while still maintaining a low rate of acute complications. Also, the rate of TTI visualization was observed to be higher with the last catheter’s generation.
The data is owned by the hospital centers and is processed by Medtronic in accordance with current regulations on data processing in pseudonymized form to enable the provision of the service.