Treat More AF Patients Efficiently

Cryoballoon Learning Curve

There are currently 33 million people estimated to have Atrial Fibrillation (AF) globally, with 14-17 million AF patients anticipated in Europe by 2030.It is estimated that it costs €18 billion annually to treat AF across the UK, Germany, France, Spain, and Italy, most of which is due to hospitalisations.2

It can, therefore, be difficult for hospitals to respond to the increased demand for AF ablations in cases when there are budget limitations, limited staff and cath lab availability, and a high total cost of care per patient.

Cryoballoon has proven to be a significantly shorter and more reproducible procedure than radiofrequency (RF), which can result in:

  • 93% less cumulative overtime hours
  • 47% more days with time for extra cath lab cases 3


Watch Prof. Carlo de Asmundis summarise the findings from his latest studies about the impact of AF procedure duration predictability on EP lab resource needs and the learning curve associated with Cryoballoon.

Click here to access Prof de Asmundis’ “Why the Distribution Matters” publication abstract.

Click here to access Prof de Asmundis’ “Learning curve using the second-generation cryoballoon ablation” publication abstract.

Providencia et al. 2016 also demonstrated that Cryoballoon ablation has less inter-operator and inter-centre outcome variability compared to point-by-point RF ablation4

Click here to access the publication abstract.

Treat More Patients with an Efficient AF Ablation Procedure

 Testimonial: Challenging Clinical Routines

Watch this video to learn how the EP team at Catharina Hospital in Eindhoven, NL increased the number of AF ablations performed per day from three to five and implemented same-day discharge, whilst improving their quality of care. The tips from this team can help you understand how you can treat more AF patients within a specific timeframe with existing resources.

Optimise EP Lab Resources

Watch the video below & learn how Prof. Joachim Ehrlich and his team at St. Josefs-Hospital in Wiesbaden, Germany doubled the number of AF ablation procedures per day within one year. They even performed eight AF ablations in one day on one occasion.


Due to the COVID-19 pandemic, elective procedures such as AF ablation were cancelled or postponed. As with many other hospitals, the St. Josefs-hospital in Wiesbaden, Germany experienced a huge backlog of AF procedures. To overcome this backlog and reduce the waiting list for AF procedures, Prof. Ehrlich and his team decided to dedicate a row of cryo days early in June 2020. For these days they increased the case capacity from usual 6 up to 10 and scheduled 27 patients within 3 days.

White Paper: Unlock EP Lab Capacity

In order to meet the growing demand for AF ablations, despite  resource constraints, Dr. Brusich and the team at University Clinical Centre Rijeka in Croatia optimised cath lab resources with careful planning and efficient procedures, such as Cryoballoon ablation. Such efforts enabled the team to avoid staff overtime and to perform four AF ablations and four complex device-related procedures in one cath lab in a single day.



Baker, C. House of Commons Library Briefing Paper. NHS Hey Statistics: England, May 2018. Number 7281, 21 May 2018


Mantovani L, et al. The burden of atrial fibrillation in the more populated European countries: perspectives from the GARFIELD-AF registry. Abstract presented ESC Congress 2017.


Kowalski M. et al. J Invasive Cardiol. 2016;28(5):176-82


Providencia R, et al. Results from a multicentre comparison of cryoballoon vs. radiofrequency ablation for paroxysmal atrial fibrillation: is cryoablation more reproducible? EP Europace. 2016;19(1):48-57. doi:10.1093/europace/euw080 Europace | Published on behalf of the European Society of Cardiology.

See the device manual for detailed information regarding the instructions for use, indications, contraindications, warnings, precautions, and potential adverse events. For further information, contact your local Medtronic representative and/or consult the Medtronic website at